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Titel:

Development of cell therapy medicinal products by academic institutes.

Dokumenttyp:
Journal Article; Review
Autor(en):
de Wilde, Sofieke; Guchelaar, Henk-Jan; Herberts, Carla; Lowdell, Mark; Hildebrandt, Martin; Zandvliet, Maarten; Meij, Pauline
Abstract:
In the rapidly evolving fields of cellular immunotherapy, gene therapy and regenerative medicine, a wide range of promising cell therapy medicinal products are in clinical development. Most products originate from academic research and are explored in early exploratory clinical trials. However, the success rate toward approval for regular patient care is disappointingly low. In this paper, we define strengths and hurdles applying to the development of cell therapy medicinal products in academic...     »
Zeitschriftentitel:
Drug Discov Today
Jahr:
2016
Band / Volume:
21
Heft / Issue:
8
Seitenangaben Beitrag:
1206-12
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.drudis.2016.04.016
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27117349
Print-ISSN:
1359-6446
TUM Einrichtung:
Kliniken und Institute
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