User: Guest  Login
Title:

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.

Document type:
Journal Article
Author(s):
Bartel, Sabine; Schulz, Nikola; Alessandrini, Francesca; Schamberger, Andrea C; Pagel, Philipp; Theis, Fabian J; Milger, Katrin; Noessner, Elfriede; Stick, Stephen M; Kicic, Anthony; Eickelberg, Oliver; Freishtat, Robert J; Krauss-Etschmann, Susanne
Abstract:
Asthma is highly prevalent, but current therapies cannot influence the chronic course of the disease. It is thus important to understand underlying early molecular events. In this study, we aimed to use microRNAs (miRNAs) - which are critical regulators of signaling cascades - to identify so far uncharacterized asthma pathogenesis pathways. Therefore, deregulation of miRNAs was assessed in whole lungs from mice with ovalbumin (OVA)-induced allergic airway inflammation (AAI). In silico predicted...     »
Journal title abbreviation:
Sci Rep
Year:
2017
Journal volume:
7
Pages contribution:
46026
Language:
eng
Fulltext / DOI:
doi:10.1038/srep46026
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28383034
Print-ISSN:
2045-2322
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
 BibTeX