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Document type:
Journal Article
Author(s):
D'Alessandria, Calogero; Braesch-Andersen, Sten; Bejo, Kristel; Reder, Sybille; Blechert, Birgit; Schwaiger, Markus; Bartolazzi, Armando
Title:
Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3.
Abstract:
The high prevalence of thyroid nodules in the adult population and the relatively low incidence of thyroid cancer make the preoperative identification of malignant lesions challenging. The ?-galactoside-binding protein galectin-3 is widely expressed in well-differentiated thyroid carcinomas, but not in normal thyrocytes and benign thyroid nodules. This molecule offers a candidate biomarker to improve thyroid cancer diagnosis. Here we report the development of an immunoPET approach for noninvasiv...     »
Journal title abbreviation:
Cancer Res
Year:
2016
Journal volume:
76
Journal issue:
12
Pages contribution:
3583-92
Language:
eng
Fulltext / DOI:
doi:10.1158/0008-5472.CAN-15-3046
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27216181
Print-ISSN:
0008-5472
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin
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