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Title:

Efficacy versus effectiveness of clinical genetic testing criteria for BRCA1 and BRCA2 hereditary mutations in incident breast cancer.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Nilsson, Martin P; Winter, Christof; Kristoffersson, Ulf; Rehn, Martin; Larsson, Christer; Saal, Lao H; Loman, Niklas
Abstract:
Increasing evidence supports the benefit of identifying BRCA1 and BRCA2 germline mutations in early breast cancer. Selection of patients for genetic testing is based on defined criteria taking individual and family history related factors into account. It is important to make a distinction between efficacy and effectiveness of BRCA testing criteria. Efficacy can be defined as the performance under ideal circumstances, whereas effectiveness refers to its real life performance. To allow for an unb...     »
Journal title abbreviation:
Fam Cancer
Year:
2017
Journal volume:
16
Journal issue:
2
Pages contribution:
187-193
Language:
eng
Fulltext / DOI:
doi:10.1007/s10689-016-9953-x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28120249
Print-ISSN:
1389-9600
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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