User: Guest  Login
Title:

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.

Document type:
Zeitschriftenaufsatz
Author(s):
Joyce PI, Fratta P, Landman AS, Mcgoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, Hilton H, Teboul L, Tucker J, Lionikas A, Estabel J, Ramirez-Solis R, White JK, Brandner S, Plagnol V, Bennet DL, Abramov AY, Greensmith L, Fisher EM, Acevedo-Arozena A
Abstract:
Zinc finger motifs are distributed amongst many eukaryotic protein families, directing nucleic acid-protein and protein-protein interactions. Zinc finger protein 106 (ZFP106) has previously been associated with roles in immune response, muscle differentiation, testes development and DNA damage, although little is known about its specific function. To further investigate the function of ZFP106, we performed an in-depth characterization of Zfp106 deficient mice (Zfp106(-/-)), and we report...     »
Dewey Decimal Classification:
500 Naturwissenschaften
Journal title:
Hum Mol Genet.
Year:
2016
Journal volume:
25
Year / month:
2016-01
Journal issue:
2
Pages contribution:
291-307
Fulltext / DOI:
doi:10.1093/hmg/ddv471
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26604141
Publisher:
The Author 2015. Published by Oxford University Press
Semester:
WS 15-16
TUM Institution:
Sportbiologie
 BibTeX