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Titel:

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Joyce PI, Fratta P, Landman AS, Mcgoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, Hilton H, Teboul L, Tucker J, Lionikas A, Estabel J, Ramirez-Solis R, White JK, Brandner S, Plagnol V, Bennet DL, Abramov AY, Greensmith L, Fisher EM, Acevedo-Arozena A
Abstract:
Zinc finger motifs are distributed amongst many eukaryotic protein families, directing nucleic acid-protein and protein-protein interactions. Zinc finger protein 106 (ZFP106) has previously been associated with roles in immune response, muscle differentiation, testes development and DNA damage, although little is known about its specific function. To further investigate the function of ZFP106, we performed an in-depth characterization of Zfp106 deficient mice (Zfp106(-/-)), and we report...     »
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Hum Mol Genet.
Jahr:
2016
Band / Volume:
25
Jahr / Monat:
2016-01
Heft / Issue:
2
Seitenangaben Beitrag:
291-307
Volltext / DOI:
doi:10.1093/hmg/ddv471
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26604141
Verlag / Institution:
The Author 2015. Published by Oxford University Press
Semester:
WS 15-16
TUM Einrichtung:
Sportbiologie
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