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- Dokumenttyp:
- Journal Article; Editorial Material
- Autor(en):
- Heidegger, Simon; Haas, Tobias; Poeck, Hendrik
- Titel:
- Cutting Edge in IFN Regulation: Inflammatory Caspases Cleave cGAS.
- Abstract:
- Caspases have important functions beyond their established role in driving inflammation and apoptosis. In this issue of Immunity, Wang et al. (2017) demonstrate that inflammasome-triggered caspases cleave and inactivate the DNA sensor cGAS, thus restricting the type I interferon response to cytosolic DNA.
- Zeitschriftentitel:
- Immunity
- Jahr:
- 2017
- Band / Volume:
- 46
- Heft / Issue:
- 3
- Seitenangaben Beitrag:
- 333-335
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.immuni.2017.03.004
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/28329695
- Print-ISSN:
- 1074-7613
- TUM Einrichtung:
- III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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