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Title:

The CD31 molecule: a possible neuroprotective agent in acute ischemic stroke?

Document type:
Journal Article
Author(s):
Boeckh-Behrens, Tobias; Kleine, Justus; Kaesmacher, Johannes; Zimmer, Claus; Schirmer, Lucas; Simon, Sophie; Poppert, Holger
Abstract:
The transmembrane receptor molecule CD31 is known to have immunomodulatory functions, suggesting a possible neuroprotective effect in the context of acute ischemic stroke by restricting an over-activation of secondary immunological processes. This study examines the density of CD31(+) cells in mechanically extracted thrombi of stroke patients with the aim to test whether the occurrence of CD31(+) cells was associated with a beneficial clinical outcome in those patients.Thrombi of 122 consecutive...     »
Journal title abbreviation:
Thromb J
Year:
2017
Journal volume:
15
Pages contribution:
11
Language:
eng
Fulltext / DOI:
doi:10.1186/s12959-017-0134-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28413360
Print-ISSN:
1477-9560
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer)
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