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Title:

Characterizing hypoxia in human glioma: A simultaneous multimodal MRI and PET study.

Document type:
Journal Article
Author(s):
Preibisch, Christine; Shi, Kuangyu; Kluge, Anne; Lukas, Mathias; Wiestler, Benedikt; Göttler, Jens; Gempt, Jens; Ringel, Florian; Al Jaberi, Mohamed; Schlegel, Jürgen; Meyer, Bernhard; Zimmer, Claus; Pyka, Thomas; Forster, Stefan
Abstract:
Hypoxia plays an important role for the prognosis and therapy response of cancer. Thus, hypoxia imaging would be a valuable tool for pre-therapeutic assessment of tumor malignancy. However, there is no standard validated technique for clinical application available yet. Therefore, we performed a study in 12 patients with high-grade glioma, where we directly compared the two currently most promising techniques, namely the MR-based relative oxygen extraction fraction (MR-rOEF) and the PET hypoxia...     »
Journal title abbreviation:
NMR Biomed
Year:
2017
Journal volume:
30
Journal issue:
11
Language:
eng
Fulltext / DOI:
doi:10.1002/nbm.3775
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28805936
Print-ISSN:
0952-3480
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Neurochirurgische Klinik und Poliklinik
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