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Title:

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.

Document type:
Journal Article
Author(s):
Strawbridge, Rona J; Laumen, Helmut; Hamsten, Anders; Breier, Michaela; Grallert, Harald; Hauner, Hans; Arner, Peter; Dahlman, Ingrid
Abstract:
Numerous genetic loci have been associated with measures of central fat accumulation, such as waist-to-hip ratio adjusted for body mass index (WHRadjBMI). However the mechanisms by which genetic variations influence obesity remain largely elusive. Lipolysis is a key process for regulation of lipid storage in adipocytes, thus is implicated in obesity and its metabolic complications. Here, genetic variants at 36 WHRadjBMI-associated loci were examined for their influence on abdominal subcutaneous...     »
Journal title:
PLOS ONE
Journal title abbreviation:
PLoS ONE
Year:
2016
Journal volume:
11
Journal issue:
4
Pages contribution:
e0153990
Fulltext / DOI:
doi:10.1371/journal.pone.0153990
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27104953
Print-ISSN:
1932-6203
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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