Benutzer: Gast  Login
Titel:

A comprehensive computational human lung model incorporating inter-acinar dependencies: Application to spontaneous breathing and mechanical ventilation

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Roth C.J., Ismail M., Yoshihara L., Wall W.A.
Abstract:
In this article, we propose a comprehensive computational model of the entire respiratory system which allows simulating patient-specific lungs under different ventilation scenarios and provides a deeper insight into local straining and stressing of pulmonary acini. We include novel 0D inter-acinar linker elements to respect the interplay between neighboring alveoli, an essential feature especially in heterogeneously distended lungs. The model is applicable to healthy and diseased patient-sp...     »
Stichworte:
Respiratory mechanics; reduced-dimensional modeling; lung interdependence; acinar model; alveolar overstraining
Dewey Dezimalklassifikation:
620 Ingenieurwissenschaften
Zeitschriftentitel:
International Journal for Numerical Methods in Biomedical Engineering
Jahr:
2017
Band / Volume:
30
Heft / Issue:
1
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1002/cnm.2787
Status:
Verlagsversion / published
 BibTeX