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Titel:

Apoptosis and treatment of chronic allograft nephropathy with everolimus.

Dokumenttyp:
Journal Article; Article
Autor(en):
Lutz, J; Zou, H; Liu, S; Antus, B; Heemann, U
Abstract:
BACKGROUND: Chronic allograft nephropathy (CAN) is responsible for most cases of late kidney allograft loss. However, no effective treatment is available so far. Everolimus (RAD) (40-O [2-hydroxyethyl] rapamycin) is a new immunosuppressive agent with antiproliferative and apoptosis-enhancing effects. We asked whether everolimus can ameliorate CAN even at advanced stages, whether everolimus treatment affects the level of growth factor mRNA, and whether everolimus treatment affects the number of a...     »
Zeitschriftentitel:
Transplantation
Jahr:
2003
Band / Volume:
76
Heft / Issue:
3
Seitenangaben Beitrag:
508-15
Sprache:
eng
Volltext / DOI:
doi:10.1097/01.TP.0000074722.79186.A9
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12923436
Print-ISSN:
0041-1337
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann)
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