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Title:

The GISS Trial: a Phase II Prevention Trial of Screening Plus Goserelin, Ibandronate, versus Screening Alone in Premenopausal Women at Increased Risk of Breast Cancer

Document type:
Article
Author(s):
von Minckwitz, Gunter; Loibl, Sibylle; Jackisch, Christian; Paepke, Stefan; Nestle-Kraemling, Caroline; Lux, MichaelP; Maass, Nico; Schmutzler, Rita; du Bois, Andreas; Wallwiener, Diethelm; Vescia, Sabine; Budischewski, Kai; Kaufmann, Manfred
Abstract:
Background: Genetic testing for inherited mutations in breast cancer genes provides valuable information for disease prevention. Today, premenopausal women with increased risk for breast cancer have only limited nonsurgical options to reduce their risk. Methods: The GISS trial, a randomized, multicenter, open-label phase II trial, assessed the feasibility of a preventive treatment with goserelin and ibandronate for premenopausal women at increased risk for breast cancer. The primary endpoints we...     »
Journal title abbreviation:
Cancer Epidemiol Biomarkers Prev
Year:
2011
Journal volume:
20
Journal issue:
10
Pages contribution:
2141-2149
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21795500
Print-ISSN:
1055-9965
TUM Institution:
Frauenklinik und Poliklinik
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