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Title:

[u-Plasminogen activator (urinary plasminogen activator, urokinase) (uPA) and its PA-1 type 1 inhibitor are not only prognostically but also predictively significant and support clinical decisions on therapy in primary carcinoma of the breast]

Document type:
Journal Article
Author(s):
Harbeck, N; Thomssen, C
Abstract:
uPA and PAI-1 are the first novel tumor biological prognostic factors in breast cancer for which the prognostic impact has been validated at the highest level of evidence and hence all evaluation criteria for transfer into clinical practice have been fullfilled. Breast cancer patients with high uPA and/or PAI-1 levels in their primary tumor tissue have a significantly lower chance for cure than patients with low levels of both uPA and PAI-1. Our research that was honored with the Schmidt-Matthie...     »
Journal title abbreviation:
Zentralbl Gynakol
Year:
2003
Journal volume:
125
Journal issue:
9
Pages contribution:
362-7
Language:
de
Fulltext / DOI:
doi:10.1055/s-2003-43036
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14569518
Print-ISSN:
0044-4197
TUM Institution:
Frauenklinik und Poliklinik
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