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Document type:
Comparative Study; Journal Article; Article 
Author(s):
Lutz, J; Risch, K; Liu, S; Antus, B; Schmaderer, C; Roos, M; Ouyang, N; Lehmann, M; Heemann, U 
Title:
Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy. 
Abstract:
Angiotensin-II (Ang-II) type 1 (AT(1)) receptor blockers may delay the progression of chronic allograft nephropathy (CAN). However, neither the optimal time for initiating AT(1) receptor blockade in order to delay CAN potentially nor the role of Ang-II type 2 (AT(2)) receptors under AT(1) receptor blockade is known. Both AT receptors can regulate p53 expression and apoptosis. We investigated what time of initiation with AT(1) blockers most effectively delayed CAN as well as the role of the AT(2)...    »
 
Journal title abbreviation:
Kidney Int 
Year:
2006 
Journal volume:
70 
Journal issue:
Pages contribution:
1080-8 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0085-2538 
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)