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Titel:

Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy.

Dokumenttyp:
Comparative Study; Journal Article; Article
Autor(en):
Lutz, J; Risch, K; Liu, S; Antus, B; Schmaderer, C; Roos, M; Ouyang, N; Lehmann, M; Heemann, U
Abstract:
Angiotensin-II (Ang-II) type 1 (AT(1)) receptor blockers may delay the progression of chronic allograft nephropathy (CAN). However, neither the optimal time for initiating AT(1) receptor blockade in order to delay CAN potentially nor the role of Ang-II type 2 (AT(2)) receptors under AT(1) receptor blockade is known. Both AT receptors can regulate p53 expression and apoptosis. We investigated what time of initiation with AT(1) blockers most effectively delayed CAN as well as the role of the AT(2)...     »
Zeitschriftentitel:
Kidney Int
Jahr:
2006
Band / Volume:
70
Heft / Issue:
6
Seitenangaben Beitrag:
1080-8
Sprache:
eng
Volltext / DOI:
doi:10.1038/sj.ki.5001709
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16850018
Print-ISSN:
0085-2538
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann)
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