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Titel:

Phase II study of weekly oxaliplatin plus infusional fluorouracil and folinic acid (FUFOX regimen) as first-line treatment in metastatic gastric cancer.

Dokumenttyp:
Clinical Trial; Clinical Trial, Phase II; Journal Article; Article
Autor(en):
Lordick, F; Lorenzen, S; Stollfuss, J; Vehling-Kaiser, U; Kullmann, F; Hentrich, M; Zumschlinge, R; Dietzfelbinger, H; Thoedtmann, J; Hennig, M; Seroneit, T; Bredenkamp, R; Duyster, J; Peschel, C
Abstract:
Oxaliplatin plus fluorouracil/folinic acid (5-FU/FA) every 2 weeks has shown promising activity in advanced gastric cancer. This study assessed the efficacy and safety of weekly oxaliplatin plus 5-FU/FA (FUFOX regimen) in the metastatic setting. Patients with previously untreated metastatic gastric cancer received oxaliplatin (50 mg m(-2)) plus FA (500 mg m(-2), 2-h infusion) followed by 5-FU (2000 mg m(-2), 24-h infusion) given on days 1, 8, 15 and 22 of a 5-week cycle. The primary end point of...     »
Zeitschriftentitel:
Br J Cancer
Jahr:
2005
Band / Volume:
93
Heft / Issue:
2
Seitenangaben Beitrag:
190-4
Sprache:
eng
Volltext / DOI:
doi:10.1038/sj.bjc.6602697
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16012522
Print-ISSN:
0007-0920
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Medizinische Statistik und Epidemiologie
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