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Titel:

Expression of tumor necrosis factor- alpha -related apoptosis-inducing ligand and its proapoptotic receptors is down-regulated during gastric infection with virulent cagA+/vacAs1+ Helicobacter pylori strains.

Dokumenttyp:
Journal Article; Article
Autor(en):
Neu, B; Rad, R; Reindl, W; Neuhofer, M; Gerhard, M; Schepp, W; Prinz, C
Abstract:
BACKGROUND: Infection of the gastric mucosa with Helicobacter pylori leads to increased apoptosis. Cytokines and receptors of the tumor necrosis factor (TNF) family are known to be involved in this process. The role that the death-inducing TNF- alpha -related apoptosis-inducing ligand (TRAIL) and its receptors play, in the context of H. pylori infection, is unknown. METHODS: In 74 H. pylori-infected and 51 H. pylori-uninfected gastric antral biopsy specimens, levels of TRAIL mRNA and TRAIL recep...     »
Zeitschriftentitel:
J Infect Dis
Jahr:
2005
Band / Volume:
191
Heft / Issue:
4
Seitenangaben Beitrag:
571-8
Sprache:
eng
Volltext / DOI:
doi:10.1086/427510
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15655781
Print-ISSN:
0022-1899
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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