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Title:

Dendritic iodinated contrast agents with PEG-cores for CT imaging: synthesis and preliminary characterization.

Document type:
journal article
Author(s):
Fu, Y; Nitecki, DE; Maltby, D; Simon, GH; Berejnoi, K; Raatschen, HJ; Yeh, BM; Shames, DM; Brasch, RC
Abstract:
The purpose of this study was to design, synthesize, and initially characterize a representative set of novel constructs for large-molecular radiographic/computed tomography (CT) contrast agents, intended for a primarily intravascular distribution. A new assembly of well-known and biocompatible components consists of paired, symmetrical dendritic polylysines initiated from both ends of a poly(ethylene glycol) (PEG) core, yielding an array of multiple free amino groups to which were conjugated hi...     »
Journal title abbreviation:
Bioconjug Chem
Year:
2006
Journal volume:
17
Journal issue:
4
Pages contribution:
1043-56
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16848414
Print-ISSN:
1043-1802
TUM Institution:
Institut für Radiologie
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