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Title:

IL-10 increases tissue injury after selective intestinal ischemia/reperfusion.

Document type:
Evaluation Studies; Journal Article
Author(s):
Nüssler, NC; Müller, AR; Weidenbach, H; Vergopoulos, A; Platz, KP; Volk, HD; Neuhaus, P; Nüssler, AK
Abstract:
OBJECTIVE This study focused on the effect of immunoregulatory cytokines on tissue injury after intestinal ischemia/reperfusion (IR). Furthermore, the role of nitric oxide, heme oxygenase-1 (HO-1) and the transcription factor NF-kappaB/Rel in the disease process was evaluated.SUMMARY BACKGROUND DATA Oxidative stress and inflammatory gene products contribute to ischemia/reperfusion injury (IRI). However, expression of stress proteins such as the inducible nitric oxide synthase (NOS-2) and HO-1 mi...     »
Journal title abbreviation:
Ann Surg
Year:
2003
Journal volume:
238
Journal issue:
1
Pages contribution:
49-58
Language:
eng
Fulltext / DOI:
doi:10.1097/01.sla.0000074962.26074.d3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12832965
Print-ISSN:
0003-4932
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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