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Titel:

An Immunohistochemical Study on the Role of Oxidative and Nitrosative Stress in Irradiated Skin.

Dokumenttyp:
Journal Article
Autor(en):
Koerdt, Steffen; Tanner, Nadine; Rommel, Niklas; Rohleder, Nils H; Stoeckelhuber, Mechthild; Wolff, Klaus-Dietrich; Kesting, Marco R
Abstract:
The effects of ionizing radiation through the generation of free radicals, reactive aldehydes, and other oxidative and nitrosative by-products account for skin injuries as side effects of radiation therapy (RT). This study aims to identify cellular pathways in oxidative and nitrosative stress in irradiated skin using well-established marker proteins in an immunohistochemical analysis.Tissue specimens of 51 patients were obtained during operative access to the neck. Twenty patients (39.2%) receiv...     »
Zeitschriftentitel:
Cells Tissues Organs
Jahr:
2017
Band / Volume:
203
Heft / Issue:
1
Seitenangaben Beitrag:
12-19
Sprache:
eng
Volltext / DOI:
doi:10.1159/000447584
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27467524
Print-ISSN:
1422-6405
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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