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- Dokumenttyp:
- Case Reports; Journal Article
- Autor(en):
- Orban, Martin; Braun, Daniel; Sonne, Carolin; Orban, Mathias; Thaler, Raffael; Grebmer, Christian; Lesevic, Hasema; Schömig, Albert; Mehilli, Julinda; Massberg, Steffen; Hausleiter, Jörg
- Titel:
- Dangerous liaison: successful percutaneous edge-to-edge mitral valve repair in patients with end-stage systolic heart failure can cause left ventricular thrombus formation.
- Abstract:
- To evaluate the characteristics and clinical outcome of patients with new formation of left ventricular (LV) thrombus after percutaneous edge-to-edge mitral valve repair.Between 2009 and 2012 we intended to treat 150 patients with severe mitral regurgitation (MR) with percutaneous edge-to-edge mitral valve repair in our centre. Post-procedural transthoracic echocardiographic examinations scheduled during the hospital stay revealed the new formation of LV thrombi in three out of 150 patients. All three patients suffered from end-stage systolic heart failure with a LV ejection fraction (LVEF) below 20% and were successfully treated in terms of MR reduction (reduction of at least two MR grades). No thrombus formation was observed in patients with a LVEF >20% treated in our centre (a total of 136 patients). The frequency of new LV thrombus formation in the cohort of patients with a LVEF <=20% treated in our centre was 21% (three out of 14 patients).New formation of LV thrombus was detected in patients with severely depressed LVEF (<=20%) after successful reduction of MR following percutaneous edge-to-edge mitral valve repair. This phenomenon could be a play of chance, but percutaneous edge-to-edge mitral valve repair using the MitraClip¨ system is a new procedure. Special care is needed when performing new procedures, and the unexpected post-procedural finding of LV thrombus formation in approximately 20% in this cohort is worth reporting.
- Zeitschriftentitel:
- EuroIntervention
- Jahr:
- 2014
- Band / Volume:
- 10
- Heft / Issue:
- 2
- Seitenangaben Beitrag:
- 253-9
- Sprache:
- eng
- Volltext / DOI:
- doi:10.4244/EIJV10I2A41
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/24168894
- Print-ISSN:
- 1774-024X
- TUM Einrichtung:
- Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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