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Title:

The genetic etiology of periodic limb movement in sleep.

Document type:
Article; Journal Article
Author(s):
Edelson, Jacob L; Schneider, Logan D; Amar, David; Brink-Kjaer, Andreas; Cederberg, Katie L; Kutalik, Zoltán; Hagen, Erika W; Peppard, Paul E; Tempaku, Priscila Farias; Tufik, Sergio; Evans, Daniel S; Stone, Katie; Tranah, Greg; Cade, Brian; Redline, Susan; Haba-Rubio, Jose; Heinzer, Raphael; Marques-Vidal, Pedro; Vollenweider, Peter; Winkelmann, Juliane; Zou, James; Mignot, Emmanuel
Abstract:
STUDY OBJECTIVES: Periodic limb movement in sleep is a common sleep phenotype characterized by repetitive leg movements that occur during or before sleep. We conducted a genome-wide association study (GWAS) of periodic limb movements in sleep (PLMS) using a joint analysis (i.e., discovery, replication, and joint meta-analysis) of four cohorts (MrOS, the Wisconsin Sleep Cohort Study, HypnoLaus, and MESA), comprised of 6843 total subjects. METHODS: The MrOS study and Wisconsin Sleep Cohort Study (...     »
Journal title abbreviation:
Sleep
Year:
2023
Journal volume:
46
Journal issue:
4
Fulltext / DOI:
doi:10.1093/sleep/zsac121
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35670608
Print-ISSN:
0161-8105
TUM Institution:
Institut für Humangenetik; Lehrstuhl für Neurogenetik (N.N.)
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