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Titel:

Sympathetic nerve damage and restoration after ischemia-reperfusion injury as assessed by (11)C-hydroxyephedrine.

Dokumenttyp:
Journal Article
Autor(en):
Werner, Rudolf A; Maya, Yoshifumi; Rischpler, Christoph; Javadi, Mehrbod S; Fukushima, Kazuhito; Lapa, Constantin; Herrmann, Ken; Higuchi, Takahiro
Abstract:
An altered state of the cardiac sympathetic nerves is an important prognostic factor in patients with coronary artery disease. The aim of this study was to investigate regional sympathetic nerve damage and restoration utilizing a rat model of myocardial transient ischemia and a catecholamine analog PET tracer, (11)C-hydroxyephedrine ((11)C-HED).Transient myocardial ischemia was induced by coronary occlusion for 20 min and reperfusion in male Wistar rats. Dual-tracer autoradiography was performed...     »
Zeitschriftentitel:
Eur J Nucl Med Mol Imaging
Jahr:
2016
Band / Volume:
43
Heft / Issue:
2
Seitenangaben Beitrag:
312-8
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00259-015-3171-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26290424
Print-ISSN:
1619-7070
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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