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Title:

Immunity in arterial hypertension: associations or causalities?

Document type:
Journal Article; Review
Author(s):
Anders, Hans-Joachim; Baumann, Marcus; Tripepi, Giovanni; Mallamaci, Francesca
Abstract:
Numerous studies describe associations between markers of inflammation and arterial hypertension (aHT), but does that imply causality? Interventional studies that reduce blood pressure reduced also markers of inflammation, but does immunosuppression improve hypertension? Here, we review the available mechanistic data. Aberrant immunity can trigger endothelial dysfunction but is hardly ever the primary cause of aHT. Innate and adaptive immunity get involved once hypertension has caused vascular w...     »
Journal title abbreviation:
Nephrol Dial Transplant
Year:
2015
Journal volume:
30
Journal issue:
12
Pages contribution:
1959-64
Language:
eng
Fulltext / DOI:
doi:10.1093/ndt/gfv057
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25762356
Print-ISSN:
0931-0509
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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