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Titel:

Comparison of Serum Galactomannan and 1,3-Beta-D-Glucan Determination for Early Detection of Invasive Pulmonary Aspergillosis in Critically Ill Patients with Hematological Malignancies and Septic Shock.

Dokumenttyp:
Comparative Study; Evaluation Studies; Journal Article; 7-8
Autor(en):
Lahmer, Tobias; Rasch, Sebastian; Schnappauf, Christopher; Beitz, Analena; Schmid, Roland M; Huber, Wolfgang
Abstract:
Invasive pulmonary aspergillosis (IPA) is an important cause of morbidity/mortality in critically ill patients with hematological malignancies. New diagnosis strategies include the noninvasive biomarkers 1,3-beta-D-glucan (BDG) and serum galactomannan (GM).For early detection of IPA, we compared BDG Fungitell assay with GM Platelia assay.Twenty-two out of 30 patients (74 %) had elevated BDG levels (mean 306 pg/ml) beyond the cutoff of 80 pg/ml. GM levels were elevated in only 3 patients (10 %) o...     »
Zeitschriftentitel:
Mycopathologia
Jahr:
2016
Band / Volume:
181
Heft / Issue:
7-8
Seitenangaben Beitrag:
505-11
Sprache:
eng
Volltext / DOI:
doi:10.1007/s11046-016-0011-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27142781
Print-ISSN:
0301-486X
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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