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Title:

Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials.

Document type:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Howard, George; Roubin, Gary S; Jansen, Olav; Hendrikse, Jeroen; Halliday, Alison; Fraedrich, Gustav; Eckstein, Hans-Henning; Calvet, David; Bulbulia, Richard; Bonati, Leo H; Becquemin, Jean-Pierre; Algra, Ale; Brown, Martin M; Ringleb, Peter A; Brott, Thomas G; Mas, Jean-Louis
Abstract:
Age was reported to be an effect-modifier in four randomised controlled trials comparing carotid artery stenting (CAS) and carotid endarterectomy (CEA), with better CEA outcomes than CAS outcomes noted in the more elderly patients. We aimed to describe the association of age with treatment differences in symptomatic patients and provide age-specific estimates of the risk of stroke and death within narrow (5 year) age groups.In this meta-analysis, we analysed individual patient-level data from fo...     »
Journal title abbreviation:
Lancet
Year:
2016
Journal volume:
387
Journal issue:
10025
Pages contribution:
1305-11
Language:
eng
Fulltext / DOI:
doi:10.1016/S0140-6736(15)01309-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26880122
Print-ISSN:
0140-6736
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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