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Titel:

Dietary fat and gut microbiota interactions determine diet-induced obesity in mice.

Dokumenttyp:
Journal Article; Article
Autor(en):
Kübeck, Raphaela; Bonet-Ripoll, Catalina; Hoffmann, Christina; Walker, Alesia; Müller, Veronika Maria; Schüppel, Valentina Luise; Lagkouvardos, Ilias; Scholz, Birgit; Engel, Karl-Heinz; Daniel, Hannelore; Schmitt-Kopplin, Philippe; Haller, Dirk; Clavel, Thomas; Klingenspor, Martin
Abstract:
Gut microbiota may promote positive energy balance; however, germfree mice can be either resistant or susceptible to diet-induced obesity (DIO) depending on the type of dietary intervention. We here sought to identify the dietary constituents that determine the susceptibility to body fat accretion in germfree (GF) mice.GF and specific pathogen free (SPF) male C57BL/6N mice were fed high-fat diets either based on lard or palm oil for 4 wks. Mice were metabolically characterized at the end of the...     »
Zeitschriftentitel:
Mol Metab
Jahr:
2016
Band / Volume:
5
Heft / Issue:
12
Seitenangaben Beitrag:
1162-1174
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.molmet.2016.10.001
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27900259
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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