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Titel:

Immunity in arterial hypertension: associations or causalities?

Dokumenttyp:
Journal Article; Review
Autor(en):
Anders, Hans-Joachim; Baumann, Marcus; Tripepi, Giovanni; Mallamaci, Francesca
Abstract:
Numerous studies describe associations between markers of inflammation and arterial hypertension (aHT), but does that imply causality? Interventional studies that reduce blood pressure reduced also markers of inflammation, but does immunosuppression improve hypertension? Here, we review the available mechanistic data. Aberrant immunity can trigger endothelial dysfunction but is hardly ever the primary cause of aHT. Innate and adaptive immunity get involved once hypertension has caused vascular w...     »
Zeitschriftentitel:
Nephrol Dial Transplant
Jahr:
2015
Band / Volume:
30
Heft / Issue:
12
Seitenangaben Beitrag:
1959-64
Sprache:
eng
Volltext / DOI:
doi:10.1093/ndt/gfv057
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25762356
Print-ISSN:
0931-0509
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann)
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