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Titel:

CD8+ T Cells Regulate Monopoiesis and Circulating Ly6C-high Monocyte Levels in Atherosclerosis in Mice.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; 3
Autor(en):
Cochain, Clément; Koch, Miriam; Chaudhari, Sweena M; Busch, Martin; Pelisek, Jaroslav; Boon, Louis; Zernecke, Alma
Abstract:
Proinflammatory adaptive immune responses are recognized as major drivers of atherosclerotic lesion formation. Although CD8(+) T cells have recently been proposed as a proatherogenic cell subset, their full scope of actions remains to be elucidated.We here addressed the contribution of CD8(+) T cells to monocyte trafficking in atherosclerosis.We observed that CD8(+) T cells express proinflammatory cytokines (interferon-?, tumor necrosis factor-?, and interleukin-12) within atherosclerotic lesion...     »
Zeitschriftentitel:
Circ Res
Jahr:
2015
Band / Volume:
117
Heft / Issue:
3
Seitenangaben Beitrag:
244-53
Sprache:
eng
Volltext / DOI:
doi:10.1161/CIRCRESAHA.117.304611
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25991812
Print-ISSN:
0009-7330
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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