Molecular precision chemotherapy: overcoming resistance to targeted therapies?

Titel:: Molecular precision chemotherapy: overcoming resistance to targeted therapies?
Dokumenttyp:: Comment; Journal Article; Research Support, Non-U.S. Gov't; Editorial Material
Autor(en):: Burdach, Stefan
Abstract:: Cytotoxic drugs may have specific effects on oncogenes and their downstream targets. Increase of cancer cell sensitivity due to repression of an oncogene downstream target can be specifically addressed by combined precision chemotherapy, increasing the therapeutic index of chemotherapy and overcoming resistance to highly selective targeted therapies.
Zeitschriftentitel:: Clin Cancer Res
Jahr:: 2014
Band / Volume:: 20
Heft / Issue:: 5
Seitenangaben Beitrag:: 1064-6
Sprache:: eng
Volltext / DOI:: doi:10.1158/1078-0432.CCR-13-3194
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/24536061
Print-ISSN:: 1078-0432
TUM Einrichtung:: Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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