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Titel:

Genotype analysis in Hungarian patients with multiple primary melanoma.

Dokumenttyp:
journal article
Autor(en):
Hatvani, Zsófia, Z; Brodszky, Valentin, V; Mazán, Mercédesz, M; Pintér, Dóra, D; Hársing, Judit, J; Tóth, Veronika, V; Somlai, Beáta, B; Kárpáti, Sarolta, S
Abstract:
Multiple primary melanoma patients (MPMps) have better prognosis and are more prone to genetic predisposition than single melanoma patients. We aimed to compare genetic background (CDKN2A, CDK4, MITF, MC1R) of 43 Hungarian MPMps with their clinicopathological data. We observed a higher rate of synchronous first and second melanoma (MM) (49%) and a higher frequency of non-melanoma tumor co-occurrence (42%) than reported previously. CDKN2A mutation frequency was 4.7% (E69G, R99P). We identified a...     »
Zeitschriftentitel:
Exp Dermatol
Jahr:
2014
Band / Volume:
23
Heft / Issue:
5
Seitenangaben Beitrag:
361-4
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24660985
Print-ISSN:
0906-6705
TUM Einrichtung:
Institut für Radiologie
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