Benutzer: Gast  Login
Titel:

Architecture and expression of the nfatc1 gene in lymphocytes.

Dokumenttyp:
journal article
Autor(en):
Rudolf, Ronald, R; Busch, Rhoda, R; Patra, Amiya K, AK; Muhammad, Khalid, K; Avots, Andris, A; Andrau, Jean-Christophe, JC; Klein-Hessling, Stefan, S; Serfling, Edgar, E
Abstract:
In lymphocytes, the three NFAT factors NFATc1 (also designated as NFAT2), NFATc2 (NFAT1), and NFATc3 (NFAT4 or NFATx) are expressed and are the targets of immune receptor signals, which lead to a rapid rise of intracellular Ca(++), the activation of phosphatase calcineurin, and to the activation of cytosolic NFATc proteins. In addition to rapid activation of NFAT factors, immune receptor signals lead to accumulation of the short NFATc1/?A isoform in lymphocytes which controls their proliferation...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2014
Band / Volume:
5
Seitenangaben Beitrag:
21
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24550910
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie
 BibTeX