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Title:

T-Cell-Dominated Immune Response Resolves Protracted SARS-CoV-2 Infection in the Absence of Neutralizing Antibodies in an Immunocompromised Individual.

Document type:
Case Reports
Author(s):
Bunse, Till; Koerber, Nina; Wintersteller, Hannah; Schneider, Jochen; Graf, Alexander; Radonic, Aleksandar; Thuermer, Andrea; von Kleist, Max; Blum, Helmut; Spinner, Christoph D; Bauer, Tanja; Knolle, Percy A; Protzer, Ulrike; Schulte, Eva C
Abstract:
Immunocompromised individuals are at higher risk of developing protracted and severe COVID-19, and understanding individual disease courses and SARS-CoV-2 immune responses in these individuals is of the utmost importance. For more than two years, we followed an immunocompromised individual with a protracted SARS-CoV-2 infection that was eventually cleared in the absence of a humoral neutralizing SARS-CoV-2 antibody response. By conducting an in-depth examination of this individual's immune respo...     »
Journal title abbreviation:
Microorganisms
Year:
2023
Journal volume:
11
Journal issue:
6
Fulltext / DOI:
doi:10.3390/microorganisms11061562
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37375064
TUM Institution:
Institut für Virologie (Prof. Protzer); Klinik und Poliklinik für Innere Medizin II, Gastroenterologie (Prof. Schmid); Roman Herzog Comprehensive Cancer Center
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