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Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Novotny, Julia; Chandraratne, Sue; Weinberger, Tobias; Philippi, Vanessa; Stark, Konstantin; Ehrlich, Andreas; Pircher, Joachim; Konrad, Ildiko; Oberdieck, Paul; Titova, Anna; Hoti, Qendresa; Schubert, Irene; Legate, Kyle R; Urtz, Nicole; Lorenz, Michael; Pelisek, Jaroslav; Massberg, Steffen; von Brühl, Marie-Luise; Schulz, Christian
Title:
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Abstract:
Medical treatment of arterial thrombosis is mainly directed against platelets and coagulation factors, and can lead to bleeding complications. Novel antithrombotic therapies targeting immune cells and neutrophil extracellular traps (NETs) are currently being investigated in animals. We addressed whether immune cell composition of arterial thrombi induced in mouse models of thrombosis resemble those of human patients with acute myocardial infarction (AMI).In a prospective cohort study of patients...     »
Journal title abbreviation:
PLoS ONE
Year:
2018
Journal volume:
13
Journal issue:
1
Pages contribution:
e0190728
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0190728
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29293656
Print-ISSN:
1932-6203
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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