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Document type:
Journal Article
Author(s):
Ducommun, Serge; Jannig, Paulo R; Cervenka, Igor; Murgia, Marta; Mittenbühler, Melanie J; Chernogubova, Ekaterina; Dias, José M; Jude, Baptiste; Correia, Jorge C; Van Vranken, Jonathan G; Ocana-Santero, Gabriel; Porsmyr-Palmertz, Margareta; McCann Haworth, Sarah; Martínez-Redondo, Vicente; Liu, Zhengye; Carlström, Mattias; Mann, Matthias; Lanner, Johanna T; Teixeira, Ana I; Maegdefessel, Lars; Spiegelman, Bruce M; Ruas, Jorge L
Title:
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.
Abstract:
OBJECTIVE: Skeletal muscle plasticity and remodeling are critical for adapting tissue function to use, disuse, and regeneration. The aim of this study was to identify genes and molecular pathways that regulate the transition from atrophy to compensatory hypertrophy or recovery from injury. Here, we have used a mouse model of hindlimb unloading and reloading, which causes skeletal muscle atrophy, and compensatory regeneration and hypertrophy, respectively. METHODS: We analyzed mouse skeletal musc...     »
Journal title abbreviation:
Mol Metab
Year:
2024
Journal volume:
82
Fulltext / DOI:
doi:10.1016/j.molmet.2024.101912
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38458566
TUM Institution:
Professur für Vaskuläre Biologie (Prof. Maegdefessel)
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