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Document type:
Journal Article
Author(s):
Pan, Huize; Ho, Sebastian E; Xue, Chenyi; Cui, Jian; Johanson, Quinian S; Sachs, Nadja; Ross, Leila S; Li, Fang; Solomon, Robert A; Connolly, E Sander; Patel, Virendra I; Maegdefessel, Lars; Zhang, Hanrui; Reilly, Muredach P
Title:
Atherosclerosis Is a Smooth Muscle Cell-Driven Tumor-Like Disease.
Abstract:
BACKGROUND: Atherosclerosis, a leading cause of cardiovascular disease, involves the pathological activation of various cell types, including immunocytes (eg, macrophages and T cells), smooth muscle cells (SMCs), and endothelial cells. Accumulating evidence suggests that transition of SMCs to other cell types, known as phenotypic switching, plays a central role in atherosclerosis development and complications. However, the characteristics of SMC-derived cells and the underlying mechanisms of SMC...     »
Journal title abbreviation:
Circulation
Year:
2024
Journal volume:
149
Journal issue:
24
Pages contribution:
1885-1898
Fulltext / DOI:
doi:10.1161/CIRCULATIONAHA.123.067587
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38686559
Print-ISSN:
0009-7322
TUM Institution:
Professur für Vaskuläre Biologie (Prof. Maegdefessel)
 BibTeX