Benutzer: Gast  Login
Mehr Felder
Einfache Suche
Titel:

CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.

Dokumenttyp:
Journal Article
Autor(en):
Metzger, Rebecca; Winter, Lis; Bouznad, Nassim; Garzetti, Debora; von Armansperg, Benedikt; Rokavec, Matjaz; Lutz, Konstantin; Schäfer, Yvonne; Krebs, Sabrina; Winheim, Elena; Friedrich, Verena; Matzek, Dana; Öllinger, Rupert; Rad, Roland; Stecher, Bärbel; Hermeking, Heiko; Brocker, Thomas; Krug, Anne B
Abstract:
Colorectal cancer is one of the most common cancers and a major cause of mortality. Proinflammatory and antitumor immune responses play critical roles in colitis-associated colon cancer. CCL17, a chemokine of the C-C family and ligand for CCR4, is expressed by intestinal dendritic cells in the steady state and is upregulated during colitis in mouse models and inflammatory bowel disease patients. In this study, we investigated the expression pattern and functional relevance of CCL17 for colitis-a...     »
Zeitschriftentitel:
J Immunol
Jahr:
2022
Band / Volume:
209
Heft / Issue:
11
Seitenangaben Beitrag:
2227-2238
Volltext / DOI:
doi:10.4049/jimmunol.2100867
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36426975
Print-ISSN:
0022-1767
TUM Einrichtung:
Professur für Molekulare Onkologie und Funktionelle Genomik (Prof. Rad)
 BibTeX