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Titel:

The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Maier, Ann-Marie; Huth, Karsten; Alessandrini, Francesca; Schnautz, Benjamin; Arifovic, Anela; Riols, Fabien; Haid, Mark; Koegler, Anja; Sameith, Katrin; Schmidt-Weber, Carsten B; Esser-von-Bieren, Julia; Ohnmacht, Caspar
Abstract:
Allergic inflammation of the airways such as allergic asthma is a major health problem with growing incidence world-wide. One cardinal feature in severe type 2-dominated airway inflammation is the release of lipid mediators of the eicosanoid family that can either promote or dampen allergic inflammation. Macrophages are key producers of prostaglandins and leukotrienes which play diverse roles in allergic airway inflammation and thus require tight control. Using RNA- and ATAC-sequencing, liquid c...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2023
Band / Volume:
14
Volltext / DOI:
doi:10.3389/fimmu.2023.1157373
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37081886
Print-ISSN:
1664-3224
TUM Einrichtung:
Lehrstuhl für Molekulare Allergologie und Umweltforschung (Prof. Schmidt-Weber)
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