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Titel:

Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Sollinger, Daniel; Eißler, Ruth; Lorenz, Steffen; Strand, Susanne; Chmielewski, Stefan; Aoqui, Cristiane; Schmaderer, Christoph; Bluyssen, Hans; Zicha, Josef; Witzke, Oliver; Scherer, Elias; Lutz, Jens; Heemann, Uwe; Baumann, Marcus
Abstract:
Recent publications have shed new light on the role of the adaptive and innate immune system in the pathogenesis of hypertension. However, there are limited data whether receptors of the innate immune system may influence blood pressure. Toll-like receptor 4 (TLR4), a pattern recognition receptor, is a key component of the innate immune system, which is activated by exogenous and endogenous ligands. Hypertension is associated with end-organ damage and thus might lead to the release of damage-ass...     »
Zeitschriftentitel:
Cardiovasc Res
Jahr:
2014
Band / Volume:
101
Heft / Issue:
3
Seitenangaben Beitrag:
464-72
Sprache:
eng
Volltext / DOI:
doi:10.1093/cvr/cvt265
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24302630
Print-ISSN:
0008-6363
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann); Hals-Nasen-Ohrenklinik und Poliklinik
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