Molecular precision chemotherapy: overcoming resistance to targeted therapies?

Title:: Molecular precision chemotherapy: overcoming resistance to targeted therapies?
Document type:: Comment; Journal Article; Research Support, Non-U.S. Gov't; Editorial Material
Author(s):: Burdach, Stefan
Abstract:: Cytotoxic drugs may have specific effects on oncogenes and their downstream targets. Increase of cancer cell sensitivity due to repression of an oncogene downstream target can be specifically addressed by combined precision chemotherapy, increasing the therapeutic index of chemotherapy and overcoming resistance to highly selective targeted therapies.
Journal title abbreviation:: Clin Cancer Res
Year:: 2014
Journal volume:: 20
Journal issue:: 5
Pages contribution:: 1064-6
Language:: eng
Fulltext / DOI:: doi:10.1158/1078-0432.CCR-13-3194
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/24536061
Print-ISSN:: 1078-0432
TUM Institution:: Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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