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Titel:

Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; 5
Autor(en):
Projahn, Delia; Simsekyilmaz, Sakine; Singh, Smriti; Kanzler, Isabella; Kramp, Birgit K; Langer, Marcella; Burlacu, Alexandrina; Bernhagen, Jürgen; Klee, Doris; Zernecke, Alma; Hackeng, Tilman M; Groll, Jürgen; Weber, Christian; Liehn, Elisa A; Koenen, Rory R
Abstract:
Myocardial infarction (MI) induces a complex inflammatory immune response, followed by the remodelling of the heart muscle and scar formation. The rapid regeneration of the blood vessel network system by the attraction of hematopoietic stem cells is beneficial for heart function. Despite the important role of chemokines in these processes, their use in clinical practice has so far been limited by their limited availability over a long time-span in vivo. Here, a method is presented to increase ph...     »
Zeitschriftentitel:
J Cell Mol Med
Jahr:
2014
Band / Volume:
18
Heft / Issue:
5
Seitenangaben Beitrag:
790-800
Sprache:
eng
Volltext / DOI:
doi:10.1111/jcmm.12225
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24512349
Print-ISSN:
1582-1838
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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