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Title:

Interferon-regulatory factors determine macrophage phenotype polarization.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Günthner, Roman; Anders, Hans-Joachim
Abstract:
The mononuclear phagocyte system regulates tissue homeostasis as well as all phases of tissue injury and repair. To do so changing tissue environments alter the phenotype of tissue macrophages to assure their support for sustaining and amplifying their respective surrounding environment. Interferon-regulatory factors are intracellular signaling elements that determine the maturation and gene transcription of leukocytes. Here we discuss how several among the 9 interferon-regulatory factors contri...     »
Journal title abbreviation:
Mediators Inflamm
Year:
2013
Journal volume:
2013
Pages contribution:
731023
Fulltext / DOI:
doi:10.1155/2013/731023
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24379524
Print-ISSN:
0962-9351
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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