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Title:

Pattern-recognition receptor signaling regulator mRNA expression in humans and mice, and in transient inflammation or progressive fibrosis.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Günthner, Roman; Kumar, Vankayala Ramaiah Santhosh; Lorenz, Georg; Anders, Hans-Joachim; Lech, Maciej
Abstract:
The cell type-, organ-, and species-specific expression of the pattern-recognition receptors (PRRs) are well described but little is known about the respective expression profiles of their negative regulators. We therefore determined the mRNA expression levels of A20, CYLD, DUBA, ST2, CD180, SIGIRR, TANK, SOCS1, SOCS3, SHIP, IRAK-M, DOK1, DOK2, SHP1, SHP2, TOLLIP, IRF4, SIKE, NLRX1, ERBIN, CENTB1, and Clec4a2 in human and mouse solid organs. Humans and mice displayed significant differences betw...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2013
Journal volume:
14
Journal issue:
9
Pages contribution:
18124-47
Fulltext / DOI:
doi:10.3390/ijms140918124
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24009023
Print-ISSN:
1422-0067
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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