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Titel:

Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients.

Dokumenttyp:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Autor(en):
Harbeck, N; Schmitt, M; Meisner, C; Friedel, C; Untch, M; Schmidt, M; Sweep, C G J; Lisboa, B W; Lux, M P; Beck, T; Hasmüller, S; Kiechle, M; Jänicke, F; Thomssen, C
Abstract:
Final 10-year analysis of the prospective randomised Chemo-N0 trial is presented. Based on the Chemo-N0 interim results and an European Organisation for Research and Treatment of Cancer (EORTC) pooled analysis (n=8377), American Society of Clinical Oncology (ASCO) and Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) guidelines recommend invasion and metastasis markers urokinase-type plasminogen activator (uPA)/plasminogen activator inhibitor-1 (PAI-1) for risk assessment and treatment decision...     »
Zeitschriftentitel:
Eur J Cancer
Jahr:
2013
Band / Volume:
49
Heft / Issue:
8
Seitenangaben Beitrag:
1825-35
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.ejca.2013.01.007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23490655
Print-ISSN:
0959-8049
TUM Einrichtung:
Frauenklinik und Poliklinik
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