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Title:

Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells in cartilage defects: in vitro and in vivo investigations.

Document type:
journal article
Author(s):
Henning, TD; Gawande, R; Khurana, A; Tavri, S; Mandrussow, L; Golovko, D; Horvai, A; Sennino, B; McDonald, D; Meier, R; Wendland, M; Derugin, N; Link, TM; Daldrup-Link, HE
Abstract:
The purpose of this study was to (1) compare three different techniques for ferumoxide labeling of mesenchymal stem cells (MSCs), (2) evaluate if ferumoxide labeling allows in vivo tracking of matrix-associated stem cell implants (MASIs) in an animal model, and (3) compare the magnetic resonance imaging (MRI) characteristics of ferumoxide-labeled viable and apoptotic MSCs. MSCs labeled with ferumoxide by simple incubation, protamine transfection, or Lipofectin transfection were evaluated with MR...     »
Journal title abbreviation:
Mol Imaging
Year:
2012
Journal volume:
11
Journal issue:
3
Pages contribution:
197-209
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22554484
Print-ISSN:
1535-3508
TUM Institution:
Institut für Radiologie
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