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Title:

Somatic differentiation and MR imaging of magnetically labeled human embryonic stem cells.

Document type:
journal article
Author(s):
Nejadnik, H; Henning, TD; Castaneda, RT; Boddington, S; Taubert, S; Jha, P; Tavri, S; Golovko, D; Ackerman, L; Meier, R; Daldrup-Link, HE
Abstract:
Magnetic resonance (MR) imaging of superparamagnetic iron oxide (SPIO)-labeled stem cells offers a noninvasive evaluation of stem cell engraftment in host organs. Excessive cellular iron load from SPIO labeling, however, impairs stem cell differentiation. The purpose of this study was to magnetically label human embryonic stem cells (hESCs) via a reduced exposure protocol that maintains a significant MR signal and no significant impairment to cellular pluripotency or differentiation potential. h...     »
Journal title abbreviation:
Cell Transplant
Year:
2012
Journal volume:
21
Journal issue:
12
Pages contribution:
2555-67
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22862886
Print-ISSN:
0963-6897
TUM Institution:
Institut für Radiologie
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