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Titel:

Visualization of vascular inflammation in the atherosclerotic mouse by ultrasmall superparamagnetic iron oxide vascular cell adhesion molecule-1-specific nanoparticles.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Michalska, M; Machtoub, L; Manthey, HD; Bauer, E; Herold, V; Krohne, G; Lykowsky, G; Hildenbrand, M; Kampf, T; Jakob, P; Zernecke, A; Bauer, WR
Abstract:
Noninvasive imaging of atherosclerosis remains challenging in clinical applications. Here, we applied noninvasive molecular imaging to detect vascular cell adhesion molecule-1 in early and advanced atherosclerotic lesions of apolipoprotein E-deficient mice.Ultrasmall superparamagnetic iron oxide particles functionalized with (P03011) or without (P3007) vascular cell adhesion molecule-1-binding peptide were visualized by ultra high-field (17.6 T) magnetic resonance. Injection of P03011 resulted i...     »
Zeitschriftentitel:
Arterioscler Thromb Vasc Biol
Jahr:
2012
Band / Volume:
32
Heft / Issue:
10
Seitenangaben Beitrag:
2350-7
Sprache:
eng
Volltext / DOI:
doi:10.1161/ATVBAHA.112.255224
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22879583
Print-ISSN:
1079-5642
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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