Login
- Dokumenttyp:
- Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't; Comparative Study; Article
- Autor(en):
- Huober, J; Fasching, P A; Barsoum, M; Petruzelka, L; Wallwiener, D; Thomssen, C; Reimer, T; Paepke, S; Azim, H A; Ragosch, V; Kubista, E; Baumgärtner, A K; Beckmann, M W; May, C; Nimmrich, I; Harbeck, N
- Titel:
- Higher efficacy of letrozole in combination with trastuzumab compared to letrozole monotherapy as first-line treatment in patients with HER2-positive, hormone-receptor-positive metastatic breast cancer - results of the eLEcTRA trial.
- Abstract:
- The eLEcTRA trial compared efficacy and safety of letrozole combined with trastuzumab to letrozole alone in patients with HER2 and hormone receptor (HR) positive metastatic breast cancer (MBC). Patients were randomized to either letrozole alone (arm A, n = 31) or letrozole plus trastuzumab (arm B, n = 26) as first-line treatment. Additional 35 patients with HER2 negative and HR positive tumors received letrozole alone (arm C). Median time to progression in arm A was 3.3 months compared to 14.1 m... »
- Zeitschriftentitel:
- Breast
- Jahr:
- 2012
- Band / Volume:
- 21
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 27-33
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.breast.2011.07.006
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/21862331
- Print-ISSN:
- 0960-9776
- TUM Einrichtung:
- Frauenklinik und Poliklinik
BibTeX