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Title:

Impaired monocyte activation in schizophrenia.

Document type:
Journal Article; Article
Author(s):
Muller, N; Wagner, JK; Krause, D; Weidinger, E; Wildenauer, A; Obermeier, M; Dehning, S; Gruber, R; Schwarz, MJ
Abstract:
An inflammatory process is hypothesized in schizophrenia. Innate immunity, in particular the monocyte/macrophage system, has rarely been studied in this disorder, although alterations in microglia indicate a role for this system. Increased monocyte numbers have repeatedly been described. Toll-like receptors (TLRs) mediate the activation of monocytes. We studied the expression of the toll-like receptors TLR-2, TLR-3 and TLR-4 on CD14(+) monocytes in 31 schizophrenia patients and 31 sex- and age-m...     »
Journal title abbreviation:
Psychiatry Res
Year:
2012
Journal volume:
198
Journal issue:
3
Pages contribution:
341-6
Language:
eng
Fulltext / DOI:
doi:10.1016/j.psychres.2011.12.049
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22429483
Print-ISSN:
0165-1781
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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